Research studies indicate that CBD influences the endocannabinoid system of the body which is a communication network of neurotransmitters that stimulate many biological processes. Many pharmaceutical medicines while working on one particular ailment also pose a threat to the health due to some side effects which affect other parts of the body. In contrast, CBD is an all-inclusive alternative without any drug dependency or known side effects. This helps in making CBD more effective in addressing the root cause of illness as compared to other available pharma products.
What is CBD?
CBD i.e. Cannabidiol is a Phyto-cannabinoid which is found primarily in cannabis sativa and industrial hemp plants and accounts for almost 40% of the cannabis plant extract. CBD has well known medicinal properties which can cure quite a few types of physical and mental ailments in the human body. It has emerged as a therapeutic agent in numerous pathological conditions as CBD does not have any psychoactive effect on the body. This simply means that the consumption of CBD for medicinal use will only result in relief from the undesired pain and discomfort caused thereby, this will not result in any observable effect in cognitive abilities of a person. This makes it unique amongst other 112 identified cannabinoids present in cannabis plant.
Does CBD get you high?
Getting high refers to becoming intoxicated or an observable alteration in cognitive ability due to consumption of a substance. This happens due to psychoactive effect of a substance on human body which is characteristically similar to that caused by smoking Marijuana. Δ9-THC (Tetrahidrocannabinol) is the main psychoactive element of the cannabis plant. It is the primary reason behind the association of ‘high’ with the recreational use of cannabis.
CBD and Δ9-THC have the same chemical formula with different atomic arrangements. This slight variation in the chemical structure makes a difference in terms of physiological effects while Δ9-THC is psychoactive, no such effect is observed with CBD. Δ9-THC affects the body directly and its effects are much visible in nature, while CBD acts on the human body indirectly by helping restore the balance of endocannabinoid system (ECS).
CBD is non-intoxicating, it does not get you high. But it does have many beneficial medicinal and therapeutic properties. CBD reviews have shown that it is anti-inflammatory, anti-psychotic, antiemetic (effective against vomiting and nausea) and anxiolytic (relieves anxiety).
CBD can be taken in use in various ways which include oral consumption or inhalation of the vapor or as an aerosol spray into the cheek. This diversity of CBD usage results in variety of products. These products vary in their therapeutic efficacy, duration of consumption and dosage. Usage of CBD products for a patient should be specific as per the individual needs. Some of the most common forms in which CBD is consumed are as follows:
- CBD Oil – It is one of the most popular forms in use. It is made by extraction of CBD concentrate from the cannabis plant flowers, buds or leaves which is later diluted with an edible carrier oil most likely hemp seed oil or coconut oil.
It is most readily available as a distillate. For consumption, a few drops of the distillate are kept under the tongue for a few minutes which leads to absorption of the CBD into blood vessels. Oil is the most popular form of administration of CBD dosage as it allows the consumption of a large dose in an easily digestible form. It is smell free and so can also be used discretely in a social setting.
- CBD Edibles – It can also be consumed as part of edibles by making it a part of snacks and treats. These edibles take the route of digestive system to start working in the body which translates into 30 minutes to 2 hours for it to get into bloodstream. Thus, therapeutic effects are relatively slower but they persist for longer durations.
Edibles such as CBD Gummies combine savory taste with therapeutic benefits and hence these chewy candies satisfy the sweet tooth while serving medical advantages too. CBD Reviews have revealed that edibles such as CBD Gummies have started replacing the counter medications as this way of consumption feels completely natural.
- CBD Topical – CBD Creams and topical lotions help nurture and heal the skin with more localized relief as compared to other products. Most common use of CBD Creams is in healing the inflammation and reducing pain around the areas affected with chronic pain, aches or regular stiffness with near instant relief. This bypasses the digestive system and can be used directly where it is needed.
Notably, one study with rats as the subject found that CBD topical can prove to be effective on arthritis-related pain symptoms and inflammation without any observable side-effects. Initial academic research on its application in humans is also promising.
CBD and Anxiety
Anxiety is how we respond to the threats posed to us in relation to our sociological safety concerns and welfare. When we fail to manage anxiety-related responses, it may slowly give rise to anxiety-related disorders which has started affecting the health of around one fifth population of our country.
Traditional drugs like Zoloft and Prozac as well as tranquilizers act via Selective Serotonin Reuptake Inhibition (SSRI) mechanism. Some of these do not turn out to be effective while the patient has to deal with side effects and sometimes addiction, which is far worse. In response to this, alternative treatments like CBD have garnered interest among the patients and scientists.
Experimentation on animals and evidence from clinical studies suggest that CBD can turn out to a safe and effective measure to tackle anxiety-related disorders. Animal studies suggest that CBD acts by a combined effect of fast onset of antidepressant action with simultaneous anxiolytic properties and in some cases, it affects serotonin faster than the SSRI mechanism. Products like CBD Gummies are useful in addressing all kinds of anxiety from mild generalized anxiety to panic disorders. This is a way forward from current limitations of antidepressant medications.
CBD dosage prescription depends on the severity of the ailment and medical health of the consumer. A fascinating research on mice suggested that same dosage of same compound may have different effects at cellular and behavioral level depending upon age of the subject. CBD binds to many kinds of receptors, so a mid-sized dose can turn out to be a sweet spot. Doubling that dose might not work the way you think.
At fairly low dosage, CBD affects the receptors with highest affinity while at higher dosage, it starts to influence other systems which start showing the positive changes. One of the most commonly heard dosage recommendations is to take one dropper of CBD per day. Though, some rough guidelines may be summed up as:
- 10 – 50 mg of CBD dosage can be taken to treat anxiety depending upon level of the ailment from general anxiety (10 mg) to panic disorder (50 mg).
- 20 – 100 mg of CBD dosage may be recommended for inflammatory conditions and arthritis-related pain.
- CBD has low oral bio-availability, so taking CBD capsules in epilepsy requires higher dosage around 100-200 mg per day. Similarly, Schizophrenia patients need to take around 40-1000 mg per day.
CBD Pro’s and Con’s
CBD Reviews suggest that it affects the body functions holistically while influencing almost every ailment ranging from anxiety and depression to inflammation. Many of us have imbalances in our Endocannabinoid System (ECS) which is a network of receptors and neurotransmitters regulating our mental and physical health and bodily functions. CBD positively affects the ECS and restores the balance. It helps in neuroprotection and neurogenesis by working indirectly and affects the immune system by playing immunomodulatory role in diseases like diabetes, arthritis and sclerosis.
CBD is not known to cause any serious side effects. People with CBD sensitivity might experience mild nausea or diarrhea but this says more about low quality of safety measures and health standards by pharmaceutical company which prepared the medicine.
This can be summed up to conclude that CBD may become a panacea for many physical and mental ailments with its exhaustive list of therapeutic properties. It has a large role to play, primarily in anxiety and depression. CBD and anxiety review shows that it affects vast majority of population with near absence of effective medication. There is still a need of further clinical studies and trials to fill in the existing knowledge gaps in the effectiveness of CBD and its long-term effects on various disease profiles on case to case basis.